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Karo Pharma · Lauromacrogols 3.0% w/w + urea 5.0% w/w

E45 Itch Relief Cream

E45 Itch Relief Cream contains lauromacrogols 3.0% w/w and urea 5.0% w/w and is licensed as a General Sales List medicine (PL 50567/0013, Karo Pharma AB).

itch reliefemollientdry skinE45
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£4.99inc. VAT
Includes our pharmacist’s order check Discreet plain packaging

A quick suitability check keeps you safe; our pharmacist reviews every order before dispatch.

E45 Itch Relief Cream contains lauromacrogols 3.0% w/w and urea 5.0% w/w and is licensed as a General Sales List medicine (PL 50567/0013, Karo Pharma AB).

What is E45 Itch Relief Cream?

E45 Itch Relief Cream is used to relieve itching and irritation linked to dry skin conditions such as eczema, dermatitis and other dry, itchy skin. It moisturises while helping calm the urge to scratch.

How does it help?

It combines lauromacrogols, which have a mild local soothing action to help relieve itching, with urea, a moisturiser that helps the skin hold on to water so it feels less dry and tight.

Key benefits

  • Relieves itching from dry, eczema-prone skin
  • Moisturises with urea to reduce dryness
  • Soothing action to calm the urge to scratch
  • Suitable for regular use on dry skin
  • General Sales List medicine

Who should take care?

Always read the patient information leaflet before use. For external use only. Don't use if you're allergic to any of the ingredients. Speak to our pharmacist if you're pregnant or breastfeeding, taking other medicines, or have any ongoing health conditions, or if your skin does not improve.

Common questions

Is E45 Itch Relief Cream a steroid?
No. It contains lauromacrogols 3% and urea 5% — lauromacrogols act rather like a mild local anaesthetic to damp down itch, while urea helps the skin’s outer layer hold on to water. There’s no hydrocortisone or any other steroid in it, so it calms itch and dryness rather than treating active inflammation. Our pharmacist can tell you which you need.
Can I use it on a child?
The UK licence covers adults, older people, children and infants over one month old — so not newborns under a month. There’s no separate children’s strength: the pack leaflet gives the amount and how often, and our pharmacist can check it’s the right choice for your child’s skin before you use it.
Can I put it on broken, weeping or infected skin?
No. The licence rules it out on oozing, infected or acutely inflamed skin and on acute erythroderma, and it can irritate broken or inflamed areas. If a patch is weeping, crusting, filling with pus, hot or painful, or you feel feverish, get same-day advice from a GP or NHS 111 — infected eczema needs treating, not moisturising.
How is it different from ordinary E45 Cream?
E45 Moisturising Cream is a plain emollient — paraffins plus lanolin that soften skin and slow water loss. Itch Relief adds lauromacrogols for the itch itself and urea to help skin hold water, and it contains no lanolin, cetyl alcohol or parabens. Many people moisturise with one and keep the other for the itchiest patches. See our eczema and dermatitis range.

About this medicine

BrandE45 (Karo Pharma AB)
ContainsLauromacrogols 3.0% w/w, urea 5.0% w/w
Pack sizes50 g and 100 g (500 g pump also licensed)
Legal classGSL — General Sales List medicine
LicencePL 50567/0013
Good practiceSee our pharmacist if symptoms persist

Information leaflet

Always read the patient information leaflet before commencing treatment.

How quickly will it arrive?

Collect from pharmacy
22-24 Woodsley Rd, Leeds LS3 1DT
Usually same day after pharmacist approvalFree
Local van delivery
Within 3 miles of the pharmacy, or LS2–LS6
Order by 10am → next morning’s 10am round£1
Standard UK delivery
Royal Mail Tracked 48
2–3 working days from dispatch£3.99 free over £40
Express UK delivery
Royal Mail Tracked 24
Next delivery day from dispatch£5.49

Every order is reviewed by our pharmacist before dispatch. Full delivery details →