Weight management
Tirzepatide vs semaglutide: how the two injections differ
How Mounjaro (tirzepatide) and Wegovy (semaglutide) compare on trial results, side effects and eligibility — with an interactive BMI checker.
Tap a dose to preview the pen · the pharmacist sets your dose at consultation
New to Mounjaro? You’ll start on 2.5 mg.
from £39.75/wk · £159 per pen · 4-dose pen
£159 per month — equivalent to £39.75 per week
A once-weekly injection that acts on two appetite-regulating gut hormones (GLP-1 and GIP). Below: how it works, who it’s licensed for, and how our pharmacist-led programme keeps it safe — every patient assessed in person or by video before any treatment, in line with GPhC February 2025 guidance on the safe supply of weight-loss medicines.
Pay at checkout · no money kept if not approved · Personal pharmacist review
About the medicine
Mounjaro is the brand name for tirzepatide, a once-weekly injectable medicine that acts on two gut hormone receptors (GLP-1 and GIP). It is licensed in the UK for chronic weight management alongside diet and physical activity in adults who meet specific clinical criteria.
Mounjaro is not a quick fix and is not appropriate for everyone. It is used as part of a longer-term, clinically supervised programme — not a short-term aesthetic treatment.
Based on clinical trial data
See the average result from the largest Mounjaro trial. Your pharmacist confirms what’s suitable for you at consultation — there’s nothing to work out first.
Pharmacist-led care
The average result from the largest Mounjaro trial, shown as a share of body weight.
*Average body-weight loss with tirzepatide 15 mg in the SURMOUNT-1 trial (on-treatment analysis; NEJM 2022). Individual results vary. Prescription-only medicine — supplied only after a clinical consultation confirms it’s suitable for you.
Important: the calculators above do not approve or reject you, and the figures are indicative. Eligibility and final pricing are decided by our pharmacists after a full video consultation including BMI verification, medical-history review, and current medications check.
How your dose builds up
Most people start on 2.5 mg for the first month, then move to 5 mg — the usual dose most people stay on. Higher doses are used only if you need them. Your pharmacist sets the pace and the dose you stay on — not everyone needs the highest dose.
You start on 2.5 mg for your first month to let your body settle in — it’s a starting dose, not the one you stay on. From month 2 the usual dose is 5 mg, which many people stay on long-term. Higher doses (7.5–15 mg) are used only if you need more, stepping up by 2.5 mg no sooner than every 4 weeks and only as tolerated, up to a maximum of 15 mg. Your pharmacist decides and adjusts your dose at consultation — not everyone needs the highest dose. Source: Mounjaro official product information (SmPC).
Clear, honest pricing
Prices are shown on this page — every pen is a 4-week supply and the exact figure depends on the dose the pharmacist recommends. Mounjaro is supplied in escalating doses — typically starting at 2.5 mg per week and increasing under clinical guidance.
The price includes dispensing and your follow-up consultations. You pay at checkout; your card is authorised and only charged when the pharmacist approves, and the consultation costs nothing if treatment isn’t appropriate for you.
Be cautious of websites offering Mounjaro at very low prices without an in-person or video consultation, identity verification, or measured BMI. The MHRA has warned about counterfeit GLP-1 injections in circulation. All medicine supplied by Hyde Park Pharmacy is sourced through licensed UK wholesalers.
Tap your dose below to see the weekly and monthly price — each chip is colour-coded to its Mounjaro strength. Every pen is a 4-week (4-dose) supply; your pharmacist confirms your actual dose and plan at consultation.
Indicative pricing. Your exact plan is confirmed at your consultation, and doses are often adjusted over time.
Who it's for
Eligibility is decided by the pharmacist at consultation. As a guide, current UK clinical criteria typically require:
This list is not exhaustive. The pharmacist will review your full medical history and current medications during your consultation.
Based on clinical trial data
In the largest Mounjaro trial, average weight loss rose with the dose. These are average trial results, not a personal promise — your pharmacist sets your dose and confirms what’s right for you.
Mean body-weight reduction at 72 weeks, SURMOUNT-1 (tirzepatide), NEJM 2022. Average results in adults with an average starting weight of ~104.8 kg; individual results vary and this is not a prediction of your outcome. Prescription-only medicine — supplied only after a pharmacist consultation.
It can take a few weeks to feel the effect as the dose steps up.
As the dose increases you should see changes in weight and habits.
A period of steadier, maintained weight management.
Illustrative trajectory based on SURMOUNT-1 (NEJM 2022); results are supported by diet and physical activity. Individual results vary — your pharmacist confirms what’s suitable for you.
How it works
A confidential questionnaire — BMI, health history and medicines. About 4 minutes, no appointment needed to start.
TodayChoose your dose and pay securely. Your card is authorised — nothing is charged until the pharmacist approves, and the hold is released in full if they can't.
2 minutesEvery weight-loss patient speaks to our pharmacist — pick a video slot at checkout or come in. They verify identity, confirm height and weight, and make the clinical decision.
Usually within 1 working dayIf approved, your pen ships cold-chain by Tracked 24, local van or collection — with scheduled reviews, side-effect support and dose adjustments from the same team.
OngoingWho reviews your case
Every consultation at Hyde Park Pharmacy is reviewed personally by our prescribing pharmacists. We've served the Leeds community from Woodsley Road for years, and we treat online care with the same standard as the counter. If treatment isn't right for you, we'll tell you — and no money is kept: a payment is refunded in full, a card authorisation is simply released.
What to expect
Most side effects are mild and gastrointestinal — they tend to improve as your body adjusts. The most common are:
Less common but more serious side effects (severe abdominal pain, signs of pancreatitis, allergic reactions, vision changes if you have diabetes) require urgent medical attention. We will give you a full information leaflet and emergency guidance at your consultation.
Your safety comes first
Comparing your options
We supply two alternatives under the same pharmacist-led service — Wegovy, another once-weekly injection, and Orlistat 120 mg capsules, a non-injection option also available as branded Xenical®. The trial figures below come from separate studies, not a head-to-head — they’re averages, individual results vary, and our pharmacists confirm what’s suitable for you.
| Mounjaro You’re here | Wegovy | Orlistat 120 mg | |
|---|---|---|---|
| Active ingredient | Tirzepatide | Semaglutide | Orlistat (also as Xenical®) |
| How it’s taken | Weekly injection (pre-filled pen) | Weekly injection (pre-filled pen) | Oral capsule — no needles |
| How often | Once a week | Once a week | With each main meal (up to 3× daily) |
| Avg. trial weight loss | ~21% at 72 weeks (up to ~22.5%) — SURMOUNT-1 | ~15% at 68 weeks — STEP 1 | Modest vs diet alone — XENDOS |
| Good to know | The highest average reduction shown here. | Also licensed to lower cardiovascular risk in some patients. | A well-established, non-injection option. |
| Price | from £159 / month | from £100 / month | Xenical® £68.99 (84 capsules) · generic priced at consultation |
| Explore | — | View Wegovy → | Start Orlistat consultation → |
Prescription-only medicines, shown here for information — not promotion. Figures are trial averages from separate studies and your own result depends on many factors. Not sure which suits you? Take the 1-minute treatment finder →
Questions, answered
No. Hyde Park Pharmacy can prescribe Mounjaro under a Patient Group Direction (PGD) after a clinical consultation, provided the pharmacist judges treatment is appropriate for you.
No. Mounjaro is a prescription-only medicine (POM). A pharmacist must consult with you, verify your identity and measure (or confirm) your BMI before any supply.
Either is acceptable. Many patients prefer to come into the pharmacy for the initial consultation, but a video consultation is available where appropriate. Identity and weight verification still apply on video — we will explain how this works when you book.
No. Following GPhC February 2025 guidance on the safe supply of high-risk medicines, an in-person or video consultation is required for Mounjaro. Self-reported weight on a form is not enough.
Mounjaro is a long-term medicine. Some patients use it for many months or longer; others use it for a shorter period as part of a broader plan. The pharmacist will discuss expected duration at consultation.
Tell us at consultation. Switching between GLP-1 medicines needs careful dose management. We won't supply Mounjaro if you're already getting another GLP-1 elsewhere unless we are coordinating the change properly.
Yes. Royal Mail Tracked 24 anywhere in the UK (fridge items always go Tracked 24), our own van across the LS2–LS6 postcodes (£1 — order by 10am for the next morning's 10am round), or free collection from 22-24 Woodsley Road. You choose at checkout.
From £39.75 per week (£159 per month) on the 2.5 mg starting dose, rising with dose to £72.25 per week (£289 per month) at 15 mg. Each pen is a 4-dose (4-week) supply. Your exact plan is confirmed at your free consultation, and doses are often adjusted over time.
In the largest trial (SURMOUNT-1), average weight loss over 72 weeks was 16% at the 5 mg dose, 21.4% at 10 mg and 22.5% at 15 mg, alongside diet and physical activity. These are trial averages, not a promise — individual results vary, and your pharmacist confirms what's realistic for you.
The most common are nausea, diarrhoea or constipation, reduced appetite and tiredness in the first few weeks — usually mild, and they tend to improve as your body adjusts. Severe abdominal pain, signs of pancreatitis, allergic reactions, or vision changes if you have diabetes need urgent medical attention. We give you the full information leaflet and emergency guidance at your consultation.
No automatic approvals. No pressure. A real prescribing pharmacist reviews your case, and no money is kept if it isn't approved.
Start your consultation →GPhC-registered · Video review included · Confidential · No money kept if not approved
Prefer to talk first? Call 0113 244 1551
Pharmacist-reviewed reading
Pharmacist-reviewed explainers to help you understand your options before you book a consultation.
How Mounjaro (tirzepatide) and Wegovy (semaglutide) compare on trial results, side effects and eligibility — with an interactive BMI checker.
A pharmacist's plain-English guide to the UK's prescription weight-loss medicines — Mounjaro, Wegovy, Saxenda and Orlistat — and how the consultation works.
Regulatory information
Hyde Park Pharmacy is a registered NHS community pharmacy regulated by the General Pharmaceutical Council (GPhC).
This page provides information about a prescription-only medicine. It is not medical advice. Always discuss your full medical history with a qualified healthcare professional before starting any new treatment. If you experience side effects, report them via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk.