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Haleon · Paracetamol 500mg and caffeine 65mg

Panadol Extra Advance Tablets

Panadol Extra Advance combines paracetamol 500mg with caffeine 65mg for headache and migraine, backache, toothache, rheumatic pain and period pain, and for the symptoms of colds, flu and sore throat.

Paracetamol and caffeineHeadache and migraineCold and flu achesAge 12+
Price checker
1 pack
£3.791 pack
Includes our pharmacist’s order check Discreet plain packaging

Our pharmacist reviews every order before dispatch. Takes under 2 minutes.

Panadol Extra Advance combines paracetamol 500mg with caffeine 65mg for headache and migraine, backache, toothache, rheumatic pain and period pain, and for the symptoms of colds, flu and sore throat.

What is Panadol Extra Advance Tablets?

Panadol Extra Advance is a tablet containing paracetamol 500mg and caffeine 65mg. It is licensed for most painful and feverish conditions, including headache and migraine, backache, toothache, rheumatic pain and period pain, and for the symptoms of colds, flu and sore throat.

How does it help?

Paracetamol reduces the pain signals registered in the brain and spinal cord, and acts on the part of the brain that controls body temperature, which helps bring down a fever. Caffeine is included alongside the paracetamol, and the two together are a well-established painkilling combination. Adults and children aged 16 and over take two tablets up to four times a day; 12 to 15 year olds take one tablet up to four times a day. Leave at least four hours between doses.

Key benefits

  • Relieves headache and migraine, backache, toothache, rheumatic pain and period pain
  • Eases the symptoms of colds, flu and sore throat, and helps bring down a fever
  • Combines paracetamol with caffeine in one tablet
  • Can be used from age 12, at a lower dose for 12 to 15 year olds

Who should take care?

Always read the patient information leaflet before use. Do not take it with any other medicine containing paracetamol, and never take more than the stated dose (8 tablets in 24 hours for those aged 16 and over, 4 tablets for 12 to 15 year olds) - a paracetamol overdose can cause serious liver damage even if you feel well at the time. Because of the caffeine, it should not be used if you are pregnant or breastfeeding, and you should avoid having a lot of tea, coffee or energy drinks while taking it. Speak to us first if you have liver or kidney problems. Not recommended for children under 12. Our pharmacist checks it is right for you before it is supplied.

About this medicine

Active ingredientsParacetamol 500mg and caffeine 65mg per tablet
Pack size16 tablets
Legal categoryGeneral Sales List (GSL)
Suitable forAdults and children aged 12 and over

Information leaflet

Always read the patient information leaflet before commencing treatment.

The leaflet for this exact product is inside the pack. If you have lost it, ask our pharmacist and we will print it for you.

How quickly will it arrive?

Collect from pharmacy
22-24 Woodsley Rd, Leeds LS3 1DT
Usually same day after pharmacist approvalFree
Local van delivery
LS2–LS6 postcodes
Order by 10am → next morning’s 10am round£1
Standard UK delivery
Royal Mail Tracked 48
2–3 working days from dispatch£3.99 free over £40
Express UK delivery
Royal Mail Tracked 24
Next delivery day from dispatch£5.49

Every order is reviewed by our pharmacist before dispatch. Full delivery details →