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Karo Pharma · White soft paraffin, light liquid paraffin, anhydrous lanolin

E45 Moisturising Cream

E45 Cream is an emollient cream licensed as a General Sales List medicine (PL 50567/0011, Karo Pharma AB), containing lanolin, light liquid paraffin and white soft paraffin.

emollientdry skineczemaE45
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Quantity · our pharmacist checks every order
£2.99inc. VAT
Includes our pharmacist’s order check Discreet plain packaging

A quick suitability check keeps you safe; our pharmacist reviews every order before dispatch.

E45 Cream is an emollient cream licensed as a General Sales List medicine (PL 50567/0011, Karo Pharma AB), containing lanolin, light liquid paraffin and white soft paraffin.

What is E45 Moisturising Cream?

E45 Cream is an emollient (moisturiser) for dry, rough or flaky skin, including conditions such as eczema, dermatitis and ichthyosis. It helps soothe and rehydrate skin that has lost its natural moisture.

How does it help?

Its blend of paraffins and lanolin softens the skin and forms a protective layer that helps reduce water loss, keeping the skin moisturised.

Key benefits

  • Moisturises dry, rough and flaky skin
  • Helps soothe eczema and dermatitis
  • Reduces water loss from the skin
  • Can be used regularly as needed
  • A long-established emollient

Who should take care?

Always read the patient information leaflet before use. This product contains lanolin, which may cause a skin reaction in some people. Don't use if you're allergic to any of the ingredients. Speak to our pharmacist if you're pregnant or breastfeeding, taking other medicines, or have any ongoing skin conditions.

Common questions

What’s the difference between E45 Cream and E45 Lotion?
Both are E45 emollients, but the cream is a licensed medicine (PL 50567/0011) while the lotion isn’t — and the cream is the richer of the two, built on white soft and light liquid paraffin. Richer creams tend to suit rough, flaky patches; the lighter lotion spreads more easily over large areas. Plenty of people keep both. Compare our moisturiser range.
Can I use E45 Cream if I’m allergic to lanolin?
No. E45 Cream contains anhydrous lanolin at 1%, so it isn’t suitable if you react to lanolin or wool alcohols. The licence also flags cetyl alcohol, which can cause contact dermatitis, and parabens, which can cause allergic reactions. Tell our pharmacist about any skin allergies and we can point you to a lanolin-free emollient instead.
Why does the pack warn about naked flames?
Because paraffin-based emollients soak into fabric. The cream isn’t flammable on your skin, but clothing, bedding and dressings that have absorbed it catch fire far more easily — a serious burn risk. Don’t smoke or sit close to an open flame while wearing it, and change and wash bedding and nightwear regularly. The NHS gives the same warning for emollients generally.
When should I see someone rather than keep moisturising?
If a patch blisters, weeps, crusts or fills with pus, feels hot, painful or swollen, or suddenly spreads — or you feel unwell or feverish — get same-day advice from a GP or NHS 111, as that can mean infected eczema. It’s also worth a conversation if skin isn’t settling despite daily emollient use. See our eczema and dermatitis range.

About this medicine

BrandE45 (Karo Pharma AB)
ContainsLanolin, light liquid paraffin, white soft paraffin
Pack sizes50 g, 125 g and 350 g
Legal classGSL — General Sales List medicine
LicencePL 50567/0011

How quickly will it arrive?

Collect from pharmacy
22-24 Woodsley Rd, Leeds LS3 1DT
Usually same day after pharmacist approvalFree
Local van delivery
Within 3 miles of the pharmacy, or LS2–LS6
Order by 10am → next morning’s 10am round£1
Standard UK delivery
Royal Mail Tracked 48
2–3 working days from dispatch£3.99 free over £40
Express UK delivery
Royal Mail Tracked 24
Next delivery day from dispatch£5.49

Every order is reviewed by our pharmacist before dispatch. Full delivery details →